Journal of Dermatological Science(2019)
Optimum wavelength characteristics for phototherapy utilizing deep ultraviolet light-emitting diodes
Hideyuki Masuda1,2, Makoto Kimura1,2, Akimichi Morita1
1 Department of Geriatric and Environmental Dermatology, Nagoya City University,Graduate School of Medical Sciences, Nagoya, Japan
2 USHIO INC, Tokyo, Japan
Lamps have been used as the light source for ultraviolet phototherapy devices. As with general lighting and industrial applications, there is a trend toward LEDs. LEDs have numerous advantages such as wavelength selectivity, long life, low power consumption, and mercury-free. On the other hand, there are issues related to differences in spectral distribution from conventional light sources. While narrowband UVB and excimer light have a full width half maximum (FWHM) of less than 5 nm, deep UV LEDs in principle have a width of about 15 nm. We investigated the optimum optical properties using Jurkat cells as an in-vitro model of T cell-associated diseases and examined apoptosis and DNA damage.
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